Vaccine Initiative

A new funding/supply mechanism has been developed to provide vaccines to developing countries This is called "Advanced Market Commitments for vaccines".

This AMC is an intriguing and big-scale system that, if I understand it correctly, takes up-front dollars from interested developing countries to provide financial down-payments to provide lower cost, set-priced vacccines. The down-payment is subsidized by other organizations (i.e. World Bank, Donors). In this way the manufacturers receive a financial guarantee and they in turn guarantee production of a certain # of vaccines (i.e. pneumococcal) to be sold at a fixed, lower price.

The first AMC is for Pneumococcal vaccine. Here's an explanation from the website:
"The Pneumococcal AMC Structure
The Advance Market Commitment pilot engages donors (five governments and the Bill & Melinda Gates Foundation), developing country governments, and GAVI Alliance members the World Bank, the World Health Organization, UNICEF and the vaccine industry to provide millions of pneumococcal vaccines to children in the developing world, 10-15 years before these life-saving vaccines would ordinarily been made available."

The graphic shown at this link portrays the arrangement for Pneumococcal vaccine.