Thursday, January 21, 2010

Haiti news

From USAID on Twitter: PaP airport has received flights from: Belgium-Bolivia-Brazil-Canada-Cuba-France-Mexico-Portugal-Spain-Sweden-Turkey-US-Ukraine, & the UN

From the White House:
The USNS Comfort arrived in Haiti today. The Comfort brings a hospital with a capacity for over 1,000 beds on board and has already started to receive patients by helicopter.
The airfield is open for 24/7 operations – 153 flights were expected for today. The U.S. was using 38 of those slots.
  • The major focus of military efforts is establishing water distribution sites, and delivering fuel, food, and medicine.
  • As of January 20, approximately 11,500 military personnel (2,000 ashore and 9,500 afloat) are a part of the relief effort.
  • To date, more than 6,174 Americans have been evacuated.

Saturday, January 16, 2010

USAID update on Health in Haiti

On January 15 at 1800 hours local time, four of the five 35-member U.S. Department of Health and Human Services (HHS) Disaster Medical Assistance Teams (DMATs) arrived in Port-au-Prince to commence rapid response medical care operations, as had a 35-member International Medical Surgical Response Team and a 35-member Incident Response Team. The aircraft transporting the remaining DMAT and a Disaster Mortuary Operational Response Team was diverted to Turks and Caicos due to air traffic congestion. The group is scheduled to depart for Haiti later on January 15.

 According to PAHO, at least eight hospitals and/or health centers are unable to function due to earthquake-related damage. Functioning health facilities are overwhelmed, forcing individuals to seek treatment in makeshift areas.
At least 13 countries in North and South America have confirmed the deployment of medical teams, and 24 international search and rescue teams are operating in Haiti, with four additional teams en route.


Health and Human Services (HHS) and USAID are recommending donations to Red Cross and CIDI.org (Center for International Disaster).

Thursday, December 10, 2009

Thoughts on H1N1 resposne

There's a really good editorial in the latest NEJM that reviews the US response to the H1N1 virus.
The Need for Science in the Practice of Public Health
Nicole Lurie, M.D., M.S.P.H.

In short, the US response revealed several "areas for improvement", including the turn-around time for the flu vaccine production and distribution, and evidence-based analysis of decisions to shut down schools etc.

The take-home message:
"We will all have the opportunity to learn lessons from the 2009 pandemic H1N1 virus. Although we would like to believe that pandemics occur rarely and that we have plenty of time until the next one, new infectious diseases, as well as other kinds of threats, can emerge at any time. One challenge will be to continue to invest in science — whether that means basic virology; surveillance; mitigation measures; vaccine development, manufacture, and distribution; operations and logistics; or communication — so that when the next pandemic or other emerging infectious disease appears, we will have the data we need to make informed decisions about how to confront it. A second challenge will be to strengthen the nation's public health infrastructure so that we can rapidly turn scientific knowledge into action."

Tuesday, October 27, 2009

Trachoma

PLoS Neglected Tropical Diseases has a review on the global burden of trachoma.


Here's the abstract:
Trachoma is the commonest infectious cause of blindness worldwide. Recurrent infection of the ocular surface by Chlamydia trachomatis, the causative agent, leads to inturning of the eyelashes (trichiasis) and blinding corneal opacification. Trachoma is endemic in more than 50 countries. It is currently estimated that there are about 1.3 million people blind from the disease and a further 8.2 million have trichiasis. Several estimates for the burden of disease from trachoma have been made, giving quite variable results. The variation is partly because different prevalence data have been used and partly because different sequelae have been included. The most recent estimate from the WHO placed it at around 1.3 million Disability-Adjusted Life Years (DALYs). A key issue in producing a reliable estimate of the global burden of trachoma is the limited amount of reliable survey data from endemic regions.

Monday, October 26, 2009

Flu....in action

This is a really great video that shows how the flu virus (or any aerosolized virus, for that matter) gets into cells, replicates, and then is released again. Check it out!
http://www.npr.org/templates/story/story.php?storyId=114075029&ft=1&f=103

Monday, October 5, 2009

Ignoring Patents in Ecuador by Sean Boley, MSII

Within the last few days, Raphael Correa, the president of Ecuador, made a statement encouraging domestic pharmaceutical companies to ignore drug patents and produce drugs that are still protected by international agreements. He said that this move was “in the name of human health.” Certainly, his thought is that by allowing local companies to manufacture drugs that are currently on patent in country, prices will decrease dramatically for sick Ecuadorians. As of now, there has been little comment from the major pharmaceutical companies, most likely because the country of thirteen and a half million people represents a small drop in the bucket of drug expenditures. Nevertheless, I would expect some generalized outrage from the companies if only because of the signal it sends to other nations considering similar moves.
At first glance, I thought that this move was generally a reasonable one. After all, our own personal experience revealed that the Ecuadorian people desperately need access to reasonably priced medicines. We saw how many sick individuals would pay for medication by the pill at the local pharmacy and quit when the symptoms subsided. Many more would not even buy the pills at all, letting the disease linger. Surely if the local pharmacies could sell locally manufactured medications at a discounted (generic) price, more people would be able to afford complete courses of treatment. Ultimately, this would lead to a healthier and more productive Ecuador.
After further consideration, I began to question such a policy. First of all, the only drugs that this would affect would be those that are on patent. Of the most commonly prescribed drugs, very few of them do not already have generics available or have generic alternatives available. In Ecuador, many of their problems are with GI or parasitic infections. Most, if not all, of the drugs to treat these conditions are already off patent. The drugs that are still on patent, are often minor adjustments to preexisting drugs marketed for the sole purpose of extending the drug companies monopoly on the medication.
Therefore, I question how much of an effect on prices and affordability this move will have. Sure, local pharmaceutical companies can begin to offer new, ‘state of the art’ drugs like losartan at reduced prices in the country, but does this significantly improve a country whose major cause of life years lost is lower respiratory infections ? Does this affect the average Ecuadorian who could use a prescription for an NSAID for his chronic back pain from working in the fields all day? More research into how much the ignoring of patents will affect the survival and morbidity of the average Ecuadorian is warranted.
If anyone is greatly affected by this, it will probably not be the average low class Ecuadorian who needs affordable access to antibiotics and antiinflammatory drugs. Rather, it is the upper class individuals in the private clinics whose problems closely mirror the medical problems in the more developed parts of the world: diabetes, hypertension, and heart disease. The medications for these ailments are the ones that still on patent because they are the ones that make the most money for the pharmaceutical industry. Therefore, I am afraid that this move by Correa, which on the surface seems to be for the health of all Ecuadorians, is really just a mechanism by which medical, social, and health inequalities in the country will be perpetuated.

By Sean Boley, MSII